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. 2019 Oct 14;25(38):5789–5799. doi: 10.3748/wjg.v25.i38.5789

Figure 3.

Figure 3

miR-490-3p directly targets HDAC2. A: The binding sites between miR-490-3p and HDAC2; B: Luciferase reporter assay; C: miR-490-3p regulated HDAC2 expression in HuH-1 cells; D: miR-490-3p regulated HDAC2 expression in HuH-1 cells; E: HDAC2 expression in 33 randomly selected hepatocellular carcinoma tissues and normal tissues; F: HDAC2 was negatively correlated with miR-490-3p in 33 randomly selected HCC tissues; G: lncRNA-SNHG15 was positively correlated with HDAC2 in 33 randomly selected HCC tissues. Untreated cells were used as control (NC). bP < 0.01. miR-490-3p: Hsa-miR-490-3p; HDAC2: Histone deacetylase 2; HuH-1: Hepatocellular carcinoma cell line; HCC: Hepatocellular carcinoma; SNHG15: Small nucleolar RNA host gene 15.