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. 2019 Oct 15;14:8285–8302. doi: 10.2147/IJN.S215142

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© 2019 Mahalunkar et al.

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Folic acid–curcumin–gold–polyvinylpyrrolidone nanoconjugates (FA–CurAu-PVP NCs) inhibit migration of breast cancer cells. (A) Confluent monolayer of MDA-MB-231 cells wounded with constant width and treated with FA–CurAu-PVP NCs (0–20 µg/mL) for 18 h. Photographs of wounds were taken at T=0 and 18 h. (B) Confluent monolayer of 4T1 cells wounded with constant width and treated with FA–CurAu-PVP NCs (0–10 µg/mL) for 6 h. Photographs of wounds were taken at T=0 and 6 h. Migrated distances were measured using Image-Pro Plus software and analyzed statistically and presented graphically using SigmaPlot software. Values are presented as mean ± SEM of three independent experiments.