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. 2019 May 17;62(10):367–373. doi: 10.3345/kjp.2019.00178

Table 1.

The differences between “old” versus “new” bronchopulmonary dysplasia

Contents Old (or classic) BPD New BPD
Infants at risk Moderately preterm infants Extremely preterm infants
Clinical characteristics Presurfactant era Postsurfactant era
Prolonged invasive ventilation with high inspired oxygen Gentle or noninvasive ventilation
Severe airway injury Interfere with lung development
Pathological aspects Interstitial and alveolar edema Arrested acinar development
Intense airway inflammation Less prominent inflammation
Lung parenchymal fibrosis Less fibrosis
Metaplasia of the respiratory epithelium Alveolar hypoplasia with fewer and larger alveoli
Pulmonary artery smooth muscle hypertrophy Abnormal and fewer vascular arteries growth
Radiologic findings Cystic emphysema Diffuse haziness
Overinflated lung filed Decreased lung field
Alveolar septal fibrosis

BPD, bronchopulmonary dysplasia.