Table 1.

The denaturing temperatures (Tm °C) of TTR proteins measured with differential scanning calorimetry (DSC) (60°C/h).

TTR protein	Buffer condition
	PBS	PBS containing 5% DMSO	PBS containing 5% DMSO and tafamidis
WT‐TTR	101.1 ± 0.3	97.2 ± 0.1	103.8 ± 0.5
V30M‐TTR	92.8 ± 0.1	89.2 ± 0.1	94.8 ± 0.1
L55P‐TTR	97.0 ± 0.2	92.3 ± 0.1	97.0 ± 0.1
A97S‐TTR	98.5 ± 0.1	93.9 ± 0.3	100.0 ± 0.3
R104H‐TTR	101.3 ± 0.1	97.6 ± 0.1	103.5 ± 0.1
T119M‐TTR	102.3 ± 0.1	98.2 ± 0.1	102.2 ± 0.2