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. 2019 Sep 23;34(40):e261. doi: 10.3346/jkms.2019.34.e261

Table 4. Serial renal function changes and comparison for matched pairs within each group.

Variables Baseline After 12 hr P valuea Effect size (d) Baseline After 48 hr P valuea Effect size (d) Baseline After 1 mon P valuea Effect size (d)
Cr, mg/dL
Control 1.51 ± 0.35 1.32 ± 0.29 < 0.001 −0.57 1.54 ± 0.38 1.53 ± 0.67 0.913 −0.02 1.52 ± 0.38 1.62 ± 0.57 0.125 0.20
Sarpogrelate 1.71 ± 0.72 1.61 ± 0.75 0.041 −0.13 1.78 ± 0.72 1.84 ± 0.91 0.361 0.07 1.65 ± 0.57 1.63 ± 0.65 0.853 −0.03
eGFR, mL/min/1.73m2
Control 47.1 ± 9.8 54.7 ± 11.7 < 0.001 0.68 46.4 ± 10.1 50.6 ± 15.3 0.066 0.31 47.1 ± 10.2 46.0 ± 14.5 0.590 −0.04
Sarpogrelate 42.0 ± 14.9 45.6 ± 17.6 0.013 0.21 40.3 ± 14.6 39.9 ± 18.3 0.834 −0.02 42.6 ± 14.4 44.7 ± 19.7 0.437 0.12

Cr = creatinine, eGFR = estimated glomerular filtration rate.

aP value for the paired t-test.