Figure 17. Timing of dengue case notifications January 2000 – March 2019 from Wolbachia intervention areas, relative to Wolbachia deployments.

The date of case onset is scaled relative to the date that local Wolbachia releases were completed or, for the five central Cairns non-release areas where Wolbachia established, the inferred date when local Wolbachia frequency reached 80%. In the post-intervention period (blue shaded area), imported cases continue to occur ( B) but locally-acquired cases have been effectively eliminated ( A). The post-intervention case surveillance period is variable across the release areas, due to staggered releases from Jan 2011 to May 2017: the median post-intervention observation period is 24 months (IQR 21–41 months, range 17–96 months), as shown in the box plots. The x-axis is left-censored at 15 years pre-release (excludes 8 local cases and 5 imported cases occurring >15 years pre-release).