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Four different mouse lines of Izumo1 gene disruption. Note that the WT, v1KO and KO mouse lines have wild-type, IZUMO1_v1 knockout, and both IZUMO1_v1 and v2 knockout alleles, respectively. Corresponding to their genetic background, each allele is expressed as a plus or minus.
| WT/WT | WT/v1KO | v1KO/v1KO | v1KO/KO | |
|---|---|---|---|---|
| IZUMO1_v1 | +/+ | +/- | -/- | -/- |
| IZUMO1_v2 | +/+ | +/+ | +/+ | +/- |
