Table 2.
Anti-proliferation activity of isolated xanthones 1.
Compounds 2 | HepG2 | A549 | SGC7901 | MCF-7 |
---|---|---|---|---|
Doxorubicin 3 | 6.52 ± 0.13 | 14.03 ± 0.21 | 7.54 ± 1.11 | 4.40 ± 1.17 |
1 | 24.61 ± 1.89 | 50.67 ± 4.41 | 28.31 ± 3.10 | 17.81 ± 6.91 |
3 | 35.06 ± 2.10 | 38.14 ± 0.06 | 25.58 ± 6.99 | 38.50 ± 9.28 |
4 | 19.71 ± 6.03 | 22.27 ± 2.14 | 10.15 ± 1.30 | 10.67 ± 7.85 |
5 | 15.88 ± 6.45 | 24.99 ± 7.67 | 5.74 ± 3.02 | 7.09 ± 1.26 |
6 | 20.47 ± 2.00 | 5.29 ± 1.34 | 16.58 ± 2.64 | 5.25 ± 2.96 |
7 | 23.12 ± 1.85 | 20.46 ± 1.45 | 16.04 ± 0.29 | 47.50 ± 2.11 |
8 | 4.14 ± 0.39 | 10.54 ± 0.25 | 0.07 ± 0.01 | 2.37 ± 1.38 |
9 | 23.62 ± 2.60 | 5.61 ± 0.60 | 13.11 ± 1.88 | 13.90 ± 0.58 |
10 | 20.41 ± 0.92 | 9.28 ± 2.01 | 6.96 ± 0.73 | 9.31 ± 1.19 |
1 The results were shown as IC50 ± SD in μmol·L−1. 2 Other isolates with IC50 > 50 μmol·L−1 for all cell lines are not listed. 3 Doxorubicin was used as a positive control.