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. 2019 Sep 27;16(19):3635. doi: 10.3390/ijerph16193635

Figure 3.

Figure 3

Flavored solutions induced greater bronchodilation in newborn as compared to adult bronchial rings. Bronchial rings (BR) isolated from neonatal and adult ovine lung were treated with flavored solutions at 1:1000 dilution. (A) Menthol, strawberry, vanilla, and tobacco flavorings all induced bronchodilation of neonatal BR, while only menthol induced bronchodilation in adults (# p < 0.05 as compared to time control). Neonatal airway demonstrated significant decrease as compared to adult with both menthol and tobacco exposure (* p < 0.05 as compared to adult). Data are presented as mean + SEM. n = 3–8. (B) Representative tracing demonstrating neonatal and adult responses in BR treated with menthol flavoring (top) as compared to untreated (time control).