Table 1.
Oncogenic and Oncosuppressor exo-miRNAs and their roles in cancer progression. ↑ means Increase, ↓ means Decrease.
| Exosomal Mir | Tumor | Effect | Ref |
|---|---|---|---|
| Oncogenic mir | |||
| miR-10b | Breast cancer | Invasion ↑ | [72] |
| miR-223 | Pancreatic cancer | Invasion↑ | [73] |
| miR-32-5p | Hepatocellular carcinoma | Drug resistance ↑ | [74] |
| miR-99a-5p, miR-125b-5p | Large B-cell lymphoma | Drug resistance ↑ | [75] |
| miR-9 | Glioma | Angiogenesis ↑ | [76] |
| miR-93-5p | Oesophageal cancer | Growth ↑ | [77] |
| miR-21,miR-378e,miR-143 | Breast Cancer | EMT and stemness ↑ | [54] |
| Oncosuppressor MIR | |||
| miR-192 | Lung adenocarcinoma | Metastasis ↓ | [78] |
| miR-451a | Hepatocellular carcinoma | Apoptosis ↑, Angiogenesis ↓ | [79] |
| miR-9 | Nasopharyngeal carcinoma | Angiogenesis ↓ | [80] |
| miR-8073 | Colorectal cancer | Growth ↓ | [81] |
| miR-100 | Breast cancer | Angiogenesis ↓ | [82] |
| miR-16-5p | Mesothelioma | Growth ↓, migration ↓, invasion ↓ | [83] |
| miR-199a | Glioma | Growth ↓, migration ↓, invasion ↓ | [84] |