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. 2019 Sep 26;20(19):4771. doi: 10.3390/ijms20194771

Figure 1.

Figure 1

The proposed mechanism of cannabidiol (CBD) in inducing apoptosis. (1) CBD binds to the central and peripheral receptors on the cell membrane; (2) this results in mitochondrial stress and reactive oxygen species (ROS) production (3) leading to Noxa activation, and thus (4) the caspase cascade activation, which results in (5) apoptosis.