A |
Adenine |
AKT1 |
AKT serine/threonine kinase 1 |
ALS |
Acid-labile subunit |
APC |
Adenomatous polyposis coli |
AS |
Antisense |
BRAF |
Proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B |
BRCA2 |
Breast cancer 2 gene |
C |
Cytosine |
CACNA1G |
Calcium channel, voltage-dependent, T type alpha-1G subunit |
CAFs |
Cancer-associated fibroblasts |
CA19-9 |
Carbohydrate antigen 19-9 (cancer antigen 19-9) |
CEA |
Carcinoembryonic antigen |
CDK1 |
Cyclin-dependent kinase 1 |
CDKN2A |
Cyclin-dependent kinase inhibitor 2A |
CEACAM6 |
CEA related cell adhesion molecule 6 gene/protein |
ceRNA |
Competing endogenous RNA |
CI |
Confidence interval |
CIMP |
CpG island methylator phenotype |
CIN |
Chromosomal instability |
CMS |
Consensum molecular subtype |
CRABP1 |
Cellular retinoic acid-binding protein 1 |
CRC |
Colorectal cancer |
CRIS |
CRC intrinsic subtype |
CRND |
Colorectal neoplasia differentially expressed |
CSCs |
Cancer stem cells |
CTCF |
CCCTC-Binding Factor (Zinc Finger Protein) |
DEGs |
Differentially expressed genes |
DMR |
Differentially methylated region |
ECM |
Extracellular matrix |
EGFR |
Epidermal Growth Factor Receptor; HER1 in humans |
eIF4A3 |
Eukaryotic initiation factor 4A-III |
ERBB2 |
Erb-B2 Receptor Tyrosine Kinase |
FSCN1 |
Fascin Actin-Bundling Protein 1 |
G |
Guanine |
GF |
Growth factor |
GH |
Growth hormone |
HMGA1 |
High Mobility Group Protein A1 |
hMLH1 |
Human mutL homolog 1 |
hsa-mir-483 |
Stem-loop sequence-micro-RNA-483 |
HyMiD |
Hypermethylation of multiple iDMRs |
iDMR |
Imprinting-associated differentially methylated region |
IGF1, -2 |
Insulin growth factor 1, -2 |
IGF1R, 2R |
IGF Receptor type I, type II |
IGF2-AS |
IGF2 antisense |
IGF2R/CI-M6PR |
IGF2R/Cation-Independent Mannose-6-phosphate Receptor |
IGFBPs |
IGF binding proteins |
IMPs |
IGF2 mRNA-binding Proteins |
INPP4B |
Inositol polyphosphate-4-phosphatase, type II |
INSR/InsR-A |
Insulin receptor/IR isoform-A |
IR |
Insulin Receptor |
IRS2 |
Insulin receptor substrate 2 |
KRAS |
Proto-oncogene K-ras or Ki-ras; from Kirsten Rat Sarcoma Virus |
lncRNAs |
Long non-coding RNAs |
LOH |
Loss of heterozygosity |
LOI |
Loss of imprinting |
MAPK |
A mitogen-activated protein kinase |
MEK1/2i |
Mitogen-activated protein kinase (MAP2K, MEK, MAPKK) inhibitor |
MLH1 |
MutL homolog 1 |
MMR |
(DNA) mismatch repair |
mRNA |
Messenger RNA |
miRNA |
MicroRNA |
MMP2 |
Matrix Metallopeptidase 2, matrix metalloproteinase (MMP) gene family |
MSI |
Microsatellite instability |
MSS |
Microsatellite stable |
mTORC1/2i |
Mammalian Target of Rapamycin Complex 1/2 inhibitor |
NEUROG1 |
Neurogenin 1 |
NICTH |
Non-islet cell tumor hypoglycaemia |
PCNA |
Proliferating cell nuclear antigen |
PIK3CA |
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
PLAGL2 |
Pleomorphic adenoma gene-like 2 |
PRC2 |
Polycomb repressive complex 2 |
PTEN |
Phosphatase and tensin homolog deleted on chromosome ten |
RB |
Retinoblastoma |
RUNX3 |
Runt-related transcription factor 3 |
SCNA |
(DNA) Somatic copy number alteration |
shRNA |
Short hairpin RNA |
sIGF2R |
Soluble IGF Receptor type II |
SOCS1 |
Suppressor of cytokine signaling 1 |
SSM |
Stem/serrated/mesenchymal |
TCGA |
The Cancer Genome Atlas |
TGF-α, β |
Tumor Growth Factor α, β |
T2DM |
Type II Diabetes Mellitus |
TNM |
Tumor-Node-Metastasis |
TP53 |
Tumor gene/protein 53 |
UTR |
Untranslated region |
VEGF-A |
Vascular endothelial growth factor A |
WNT1 |
Wnt (gene wingless + integrated or int-1) Family Member 1 |