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. 2019 Oct 3;20(19):4915. doi: 10.3390/ijms20194915
A Adenine
AKT1 AKT serine/threonine kinase 1
ALS Acid-labile subunit
APC Adenomatous polyposis coli
AS Antisense
BRAF Proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B
BRCA2 Breast cancer 2 gene
C Cytosine
CACNA1G Calcium channel, voltage-dependent, T type alpha-1G subunit
CAFs Cancer-associated fibroblasts
CA19-9 Carbohydrate antigen 19-9 (cancer antigen 19-9)
CEA Carcinoembryonic antigen
CDK1 Cyclin-dependent kinase 1
CDKN2A Cyclin-dependent kinase inhibitor 2A
CEACAM6 CEA related cell adhesion molecule 6 gene/protein
ceRNA Competing endogenous RNA
CI Confidence interval
CIMP CpG island methylator phenotype
CIN Chromosomal instability
CMS Consensum molecular subtype
CRABP1 Cellular retinoic acid-binding protein 1
CRC Colorectal cancer
CRIS CRC intrinsic subtype
CRND Colorectal neoplasia differentially expressed
CSCs Cancer stem cells
CTCF CCCTC-Binding Factor (Zinc Finger Protein)
DEGs Differentially expressed genes
DMR Differentially methylated region
ECM Extracellular matrix
EGFR Epidermal Growth Factor Receptor; HER1 in humans
eIF4A3 Eukaryotic initiation factor 4A-III
ERBB2 Erb-B2 Receptor Tyrosine Kinase
FSCN1 Fascin Actin-Bundling Protein 1
G Guanine
GF Growth factor
GH Growth hormone
HMGA1 High Mobility Group Protein A1
hMLH1 Human mutL homolog 1
hsa-mir-483 Stem-loop sequence-micro-RNA-483
HyMiD Hypermethylation of multiple iDMRs
iDMR Imprinting-associated differentially methylated region
IGF1, -2 Insulin growth factor 1, -2
IGF1R, 2R IGF Receptor type I, type II
IGF2-AS IGF2 antisense
IGF2R/CI-M6PR IGF2R/Cation-Independent Mannose-6-phosphate Receptor
IGFBPs IGF binding proteins
IMPs IGF2 mRNA-binding Proteins
INPP4B Inositol polyphosphate-4-phosphatase, type II
INSR/InsR-A Insulin receptor/IR isoform-A
IR Insulin Receptor
IRS2 Insulin receptor substrate 2
KRAS Proto-oncogene K-ras or Ki-ras; from Kirsten Rat Sarcoma Virus
lncRNAs Long non-coding RNAs
LOH Loss of heterozygosity
LOI Loss of imprinting
MAPK A mitogen-activated protein kinase
MEK1/2i Mitogen-activated protein kinase (MAP2K, MEK, MAPKK) inhibitor
MLH1 MutL homolog 1
MMR (DNA) mismatch repair
mRNA Messenger RNA
miRNA MicroRNA
MMP2 Matrix Metallopeptidase 2, matrix metalloproteinase (MMP) gene family
MSI Microsatellite instability
MSS Microsatellite stable
mTORC1/2i Mammalian Target of Rapamycin Complex 1/2 inhibitor
NEUROG1 Neurogenin 1
NICTH Non-islet cell tumor hypoglycaemia
PCNA Proliferating cell nuclear antigen
PIK3CA Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PLAGL2 Pleomorphic adenoma gene-like 2
PRC2 Polycomb repressive complex 2
PTEN Phosphatase and tensin homolog deleted on chromosome ten
RB Retinoblastoma
RUNX3 Runt-related transcription factor 3
SCNA (DNA) Somatic copy number alteration
shRNA Short hairpin RNA
sIGF2R Soluble IGF Receptor type II
SOCS1 Suppressor of cytokine signaling 1
SSM Stem/serrated/mesenchymal
TCGA The Cancer Genome Atlas
TGF-α, β Tumor Growth Factor α, β
T2DM Type II Diabetes Mellitus
TNM Tumor-Node-Metastasis
TP53 Tumor gene/protein 53
UTR Untranslated region
VEGF-A Vascular endothelial growth factor A
WNT1 Wnt (gene wingless + integrated or int-1) Family Member 1