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. 2019 Oct 1;16(19):3701. doi: 10.3390/ijerph16193701

Table 6.

Rates (per 1000 children) of specific fetal alcohol spectrum disorders (FASD) diagnosis and total FASD by rural and urban residence: Western Cape Province communities: 1997–2011.

Community A Community/Region B
Sample 1 Sample 2 Sample 3 Sample 4 Sample 5 Sample 1 Sample 2
Rural Urban p ^ Rural Urban p ^ Rural Urban p ^ Rural Urban p ^ Rural Urban P ^ Rural Urban p ^ Rural Urban p ^
FAS 25.2 15.1 <0.001 23.9 17.4 <.0001 28.6 25.7 0.142 28.8 30.5 0.737 19.6 39.2 <0.001 53.1 39.7 <0.001 40.1 49.0 <0.001
PFAS * 1.0 3.0 0.002 13.0 18.4 0.001 4.9 12.8 <0.001 14.8 30.5 <0.001 19.6 58.0 <0.001 27.3 31.1 <0.001 25.6 43.5 <0.001
ARND ** 0.0 0.0 -- 3.3 7.6 <0.001 0.0 0.0 -- 14.8 16.6 0.236 11.1 22.2 <0.001 16.6 15.0 <0.001 13.8 24.2 <0.001
Total FASD 26.2 18.1 <.001 40.1 43.4 0.151 41.5 38.5 0.168 58.4 77.6 <.001 50.3 119.5 <0.001 97.0 85.7 <0.001 79.4 116.7 <0.001

* PFAS cases in Samples 1 and 2 were made retrospectively in 2003 as the diagnostic criteria were clarified. The focus at the time of examination for Samples 1 and 2 was exclusively on FAS. ** No ARND cases were diagnosed in Samples 1 and 3 because of the singular focus on FAS. The ARND cases diagnosed in Sample 2 were diagnosed retrospectively, and not at the study, as the diagnostics interview for ARND was clarified by 2008. ^z-test of proportions.