Table 1.
Quantitative summary of the protective effects of different fraction extracts of garlic on Der p–induced allergic asthma based on histological observations.
| Organ | Histopathological Findings | Groups 1 | ||||||
|---|---|---|---|---|---|---|---|---|
| Control | Der p | Der p | ||||||
| HE | DI | EA | BU | WH | ||||
| Lung | Inflammation, eosinophilic and lymphocytic cells, perivascular and per bronchial, focal | 0.0 ± 0.00 | 3.3 ± 0.19 # | 3.0 ± 0.00 | 2.5 ± 0.50 | 2.8 ± 0.19 | 2.8 ± 0.19 | 1.8 ± 0.19 * |
| Aggregation, macrophage and giant cells, alveolar, focal | 0.0 ± 0.00 | 2.5 ± 0.22 # | 2.0 ± 0.00 | 1.8 ± 0.38 | 1.8 ± 0.19 | 1.5 ± 0.22 | 0.8 ± 0.19 * | |
| Epithelial hyperplasia, bronchial, focal | 0.0 ± 0.00 | 2.0 ± 0.00 # | 2.0 ± 0.00 | 1.5 ± 0.38 | 1.5 ± 0.22 | 1.0 ± 0.31 * | 1.0 ± 0.31 * | |
| Mucification, goblet, bronchial, focal | 0.0 ± 0.00 | 2.0 ± 0.00 # | 1.8 ± 0.19 | 1.5 ± 0.38 | 1.5 ± 0.22 | 1.0 ± 0.31 * | 1.0 ± 0.31 * | |
| Brachus | Inflammation, submucosal, focal | 1.0 ± 0.00 | 3.3 ± 0.58 # | 2.3 ± 0.58 | 2.0 ± 0.82 | 2.0 ± 0.82 | 1.5 ± 0.58 | 1.3 ± 0.43 * |
1 Degree of lesions was graded from one to five depending on severity: 1 = minimal (< 1%); 2 = slight (1–25%); 3 = moderate (26–50%); 4 =moderate/severe (51–75%); 5 = severe/high (76–100%). # Statistically significant difference between control and Der p groups at p < 0.05. * Statistically significant difference between Der p and treated groups at p < 0.05.