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. 2019 Sep 26;20(19):4777. doi: 10.3390/ijms20194777

Figure 3.

Figure 3

Histology and immunohistochemistry staining of prostate on day 7 post-capsaicin injection with or without LESW treatment. (A): sham control, (B): day 7 post-capsaicin (CAP) injection showed edematous change with accumulation of inflammatory cells in the interstitial space, the effects of which were decreased by 200 and 300 shocks LESW treatment (D,E), while 100 shocks therapy (C) showed no significant effect ((F), average cell count per unit area). COX-2 and TNF-α positive inflammatory cells accumulated (red arrow) in CAP group (H,N) was significantly decreased by LESW 200 and 300 shocks treatment (L,R) (p < 0.05, CAP vs. 200 SW group; CAP vs. 300 SW group). (A–E): hematoxyline and eosin stain; (G–K): COX-2 stain; (M–Q): TNF-α stain; magnification ×100; inlet, magnification ×400; scale bars indicate 100 μm. * Statistically significant difference between groups (p < 0.05) (F,L,R).