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. 2019 Sep 26;20(19):4777. doi: 10.3390/ijms20194777

Figure 4.

Figure 4

Day 3. Western blot for detecting IL-1β, TNF-α, COX-2, IL-6, inflammasome NALP-1, caspase-1, and NGF expression in the prostate (A). Capsaicin-induced upregulation of IL-1β, COX-2, IL-6, caspase-1, and NGF expression (B,D–F,H). LESW significantly suppressed IL-1β, COX-2, caspase-1, NGF expression in a dose-dependent manner but not in IL-6, TNF-α and NALP-1 (C,E,G) (100 shocks: COX-2, caspase-1; 200 shocks: IL-1β, COX-2, caspase-1, NGF; 300 shocks: COX-2, caspase-1, NGF) *, p < 0.05; # p < 0.01; † p < 0.001; ‡ p < 0.0001.