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. 2019 Sep 30;20(19):4869. doi: 10.3390/ijms20194869

Figure 2.

Figure 2

MFSCC suppressed catabolic enzymes production in IL-1α-stimulated primary chondrocytes. The rat primary chondrocytes were treated with varying concentrations of MFSCC (0, 1, 5, and 10 μg/mL) for 24 h followed by IL-1α (10 ng/mL) stimulation for 1 h. The expression of MMP-3, MMP-13, collagen II, aggrecan, collagen I, and SOX-9 was detected by western blot (AC) and qRT-PCR (DI). The data are expressed as mean ± SEM (# p < 0.05 compared with the control group; * p < 0.05 compared with the IL-1α group).