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. 2019 Sep 22;20(19):4699. doi: 10.3390/ijms20194699

Table 2.

Characteristics of the urinary biomarkers in subclinical acute rejection (subAR).

AUC (95% CI) Cut-off Value Sensitivity (95% CI) Specificity (95% CI) Positive Predictive Value Negative Predictive Value p Value
LC3 (pg/mg creatinine) 0.725 (0.554–0.895) 517.9 0.64 (0.31–0.89) 0.78 (0.67–0.87) 0.32 0.93 0.01725
MCP-1(pg/mg creatinine) 0.688 (0.539–0.837) 226.0 0.82 (0.48–0.98) 0.57 (0.44–0.68) 0.23 0.95 0.04655
L-FABP (ng/mg creatinine) 0.606 (0.446–0.767) 7.6 0.09 (0.00–0.41) 0.88 (0.78–0.94) 0.15 1.00 0.2608
NGAL (ng/mg creatinine) 0.715 (0.589–0.842) 12.8 1.00 (0.72–1.00) 0.48 (0.36–0.60) 0.23 1.00 0.0224
HE4 (ng/mg creatinine) 0.808 (0.700–0.916) 789.1 1.00 (0.72–1.00) 0.54 (0.41–0.66) 0.26 1.00 0.001113