Table 3.
Characteristics of the urinary biomarkers in severe tubulitis (ST).
| AUC (95% CI) | Cut-off Value | Sensitivity (95% CI) | Specificity (95% CI) | Positive Predictive Value | Negative Predictive Value | p Value | |
|---|---|---|---|---|---|---|---|
| LC3 (pg/mg creatinine) | 0.584 (0.339–0.829) | 131.7 | 1.00 (0.48–1.00) | 0.24 (0.15–0.35) | 0.08 | 1.00 | 0.5313 |
| MCP-1 (pg/mg creatinine) | 0.632 (0.365–0.899) | 417.9 | 0.60 (0.15–0.95) | 0.76 (0.65–0.85) | 0.14 | 0.97 | 0.3252 |
| L-FABP (ng/mg creatinine) | 0.600 (0.388–0.812) | 7.2 | 0.20 (0.00–0.71) | 0.86 (0.76–0.93) | 0.07 | 1.00 | 0.4561 |
| NGAL (ng/mg creatinine) | 0.867 (0.745–0.989) | 23.0 | 1.00 (0.48–1.00) | 0.72 (0.60–0.82) | 0.19 | 1.00 | 0.006299 |
| HE4 (ng/mg creatinine) | 0.875 (0.731–1.018) | 1165.6 | 0.80 (0.28–0.99) | 0.84 (0.74–0.91) | 0.25 | 0.98 | 0.005248 |