Table 6.
Multivariable analyses.
| Logistic Regression 1: Taking Resistance to Treatment Based on the BPRS as the Dependent Variable | ||||
| Variable | p-Value | ORa | 95% Confidence Interval (CI) | |
| Lower Bound | Lower Bound | |||
| Time since the beginning of treatment (years) | 0.047 | 0.730 | 0.535 | 0.996 |
| Adherence to treatment score | 0.094 | 0.679 | 0.432 | 1.068 |
| Chlorpromazine equivalent daily dose (mg) | 0.062 | 1.001 | 1.000 | 1.001 |
| Variables entered in model 1: Gender, time since the beginning of treatment (years), adherence to treatment score, consumption of psychoactive substances, chlorpromazine equivalent daily dose (mg). | ||||
| Logistic Regression 2: Taking Resistance to Treatment Based on the PANSS as the Dependent Variable | ||||
| Variable | p-Value | ORa | 95% Confidence Interval (CI) | |
| Lower Bound | Lower Bound | |||
| Level of education: Secondary | 0.369 | 0.481 | 0.097 | 2.377 |
| Level of education: University | 0.042 | 11.962 | 1.095 | 130.661 |
| Family history of schizophrenic episodes | 0.043 | 4.617 | 1.048 | 20.329 |
| Time since the beginning of treatment (years) | 0.097 | 0.675 | 0.425 | 1.074 |
| Chlorpromazine equivalent daily dose (mg) | 0.020 | 1.001 | 1.000 | 1.002 |
| Variables entered in model 2: Gender, level of education, family history of schizophrenic episodes, psychotherapy, time since the beginning of treatment (years), adherence to treatment score, consumption of benzodiazepines, chlorpromazine equivalent daily dose (mg). | ||||
| Logistic Regression 3: Taking Resistance to Treatment Based on the BPRS or PANSS as the Dependent Variable | ||||
| Variable | p-Value | ORa | 95% Confidence Interval (CI) | |
| Lower Bound | Lower Bound | |||
| Time since the beginning of treatment (years) | 0.023 | 0.675 | 0.481 | 0.946 |
| Adherence to treatment score | 0.068 | 0.646 | 0.405 | 1.032 |
| Chlorpromazine equivalent daily dose (mg) | 0.026 | 1.001 | 1.000 | 1.002 |
| Family history of schizophrenic episodes | 0.088 | 2.779 | 0.858 | 9.003 |
| Variables entered in model 3: Gender, family history of schizophrenic episodes, time since the beginning of treatment (years), adherence to treatment score, consumption of psychoactive substances, chlorpromazine equivalent daily dose (mg). | ||||
Numbers in bold indicate significant associations between variables; BPRS: brief psychiatric rating scale; PANSS: positive and negative syndrome scale; ORa = adjusted odds ratio; CI = confidence interval.