Figure 2.

HM-10/10 peptide mitigates sodium iodate (NaIO₃)-induced increase in apoptosis of hfRPE cells. hfRPE cells were incubated with HM-10/10 peptide at 10 μg/mL, or NaIO₃ at either 200 μg/mL or 500 ug/mL, or treated with NaIO₃ and HM-10/10 together, for 24 h as described under Materials and Methods. Apoptosis was analyzed and quantified by TUNEL staining (lower panel). Representative images showing TUNEL-positive apoptotic nuclei (red) and DAPI (blue) in all groups (upper panel). White scale bar = 100 μm. Asterisk indicates p < 0.0036 with the Bonferroni correction.