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Knee radiographs in the antero-posterior projection. A-RX from the healthy rat paw (CLEAN); B1 and B2-RX from the rat paw with experimental model of MIA-induced osteoarthritis–saline group; C-RX, A. chica extract 450 mg/kg treated group. This analysis was performed with the knees collected on day 29 after OA induction. Arrowhead: red—indicating a remarkable narrowing of the joint space and deformity in the bone contour; green—subchondral sclerosis; orange—large osteophytes.
