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. 2019 Sep 23;20(19):4717. doi: 10.3390/ijms20194717

Figure 8.

Figure 8

Histopathological evaluation of cartilage classified using the Osteoarthritis Research Society International (OARSI) scoring system. This analysis was performed with the knees collected on day 29 after OA induction. Groups: EHA450 = with sodium monoiodoacetate-induced osteoarthritis (MIA-induced OA) 2 mg and treated with A. chica hydroalcoholic extract 450 mg/kg; CTL− = with MIA-induced OA (2 mg) and treated with 0.9% sodium chloride saline; CTL + Melox = with MIA-induced OA (2 mg) and treated with meloxicam 0.5 mg/kg; CLEAN = untreated and uninduced OA, healthy. Y-axis: Histopathological evaluation of cartilage (OARSI histological classification: Grade 0—surface intact and cartilage intact; Grade 1—surface intact; Grade 2—surface discontinuity; Grade 3—vertical fissures; Grade 4—erosion; Grade 5—denudation; and Grade 6—deformation).