Figure 5.

High tumor miR-126 levels are associated with poor survival in patients with OAC.

In 14 patients with high relative miR-126 levels in tumor (top25%), as compared to 44 patients with a median or low relative level of tumor miR-126, the average difference was 2.3-fold (P<0.001). (b) Shown is five-year overall survival of the 58 patients treated with neoadjuvant chemoradiotherapy followed by surgery. High expression level of miR-126 in tumor tissue was significantly associated with poorer survival in patients with OAC. Cox regression analysis was used (Log rank P=0.031). The number of patients in each group at 12, 24, 36, 48, and 60 months post-treatments is shown at the bottom.