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. 2019 Oct 18;10:4768. doi: 10.1038/s41467-019-12824-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Wild-type and Igll1^−/− Igll1^−/− B-1a cells have a similar V_K gene segment usage to wild-type controls and maintain V_K4-91 enrichment. Representative synthesis graphs generated from IMGT/StatClonotype that compare differences in Igk V gene segment usage between Igll1^−/− (red) versus wild-type (blue) peritoneal cavity B-1a cells CD19⁺B220^loCD5⁺ (left side) or Igll1^−/− (red) peritoneal cavity B-1a cells vs wild-type (blue) peritoneal cavity B-2 cells CD19⁺B220⁺ (right side). The red box highlights V_K4 (V_K4-91) gene segment (n = 2 independent experiments). This graph combines a bar graph for the normalized proportions of each gene segment and the differences in proportions with significance and confidence intervals (CI)