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. 2019 Oct 9;2(10):e1912831. doi: 10.1001/jamanetworkopen.2019.12831

Table 2. Association of ePWV With Different End Points in the Patients With Hypertension From SPRINTa.

Outcome No. HR per 1 SD of ePWV (95% CI) P Value
Primary outcome 558 1.30 (1.17-1.43) <.001
MI 212 1.10 (0.94-1.30) .24
Non-MI acute coronary syndrome 80 1.03 (0.78-1.36) .83
Stroke 131 1.45 (1.20-1.76) <.001
Heart failure 162 1.70 (1.42-2.04) <.001
CV death 100 1.39 (1.10-1.76) .006
Death from non-CV cause 262 1.76 (1.53-2.03) <.001
All-cause death 362 1.65 (1.46-1.86) <.001
Primary outcome or death 750 1.36 (1.25-1.48) <.001

Abbreviations: CV, cardiovascular; ePWV, estimated pulse wave velocity; HR, hazard ratio; MI, myocardial infarction; SPRINT, Systolic Blood Pressure Intervention Trial.

a

The model includes Framingham Risk Score, antihypertensive assigned treatment (intensive vs standard), the presence of clinical or subclinical CV disease, antihypertensive treatment at baseline, and systolic blood pressure at baseline and was assessed separately for each outcome.