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. 2019 Oct 10;145(12):1150–1157. doi: 10.1001/jamaoto.2019.2768

Table 5. Multivariable Model With Risk Classification System.

Variable Odds Ratio (95% CI)
30-d Severe Complicationa 90-d Mortalityb 90-d Functional Declinec,d
Risk classification system
Class I 1 [Reference] 1 [Reference] 1 [Reference]
Class II 1.87 (1.28-2.72) 3.39 (1.22-9.42) NA
Class III 4.50 (2.44-8.28) 6.67 (1.40-31.85) 2.49 (1.11-5.57)
Additional operations
No 1 [Reference] 1 [Reference] 1 [Reference]
Yes 5.04 (2.59-9.84) NA 3.24 (1.79-5.86)
Duration of surgery 1.08 (1.00-1.16) NA NA
Flap failure NA 3.63 (1.48-8.89) NA
Tumor site
Scalp, facial skin, or parotid NA NA 1 [Reference]
Maxilla, oral cavity, or oropharynx NA NA 3.07 (1.51-6.25)
Larynx, hypopharynx, or esophagus NA NA NA

Abbreviation: NA, not applicable.

a

Additional variables tested in multivariable model include ablation site, American Society of Anesthesiologists (ASA) classification, flap failure, and flap type.

b

Additional variables tested in multivariable model include additional operations, ASA classification, and flap type.

c

Additional variables tested in multivariable model include additional operations, ASA classification, flap failure, flap type, prior head and neck radiotherapy, and duration of surgery.

d

Includes 328 patients who were not dependent at baseline and were alive at 90 days.