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. 2019 Oct 21;19:972. doi: 10.1186/s12885-019-6185-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Enzalutamide inhibits TMPRSS2-ERG fusion positive cancer cell growth. a Western blot analysis of VCaP Scr shRNA and VCaP ERG shRNA cells for ERG and b-tubulin expression. ERG expression was normalized for b-tubulin and fold differences between VCaP Scr shRNA and VCaP ERG shRNA cells were shown. b Cell growth analysis of VCaP scr shRNA and VCaP ERG shRNA cells treated with 5–20 μM concentrations of enzalutamide for 3, 5 and 7 days. * Indicate the p < 0.05 between groups (DMSO vs. enzalutamide treatment) using student t-test and n = 3