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. 2019 Oct 21;19:972. doi: 10.1186/s12885-019-6185-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Enzalutamide inhibits the bone tumor growth. Enzalutamide treatment started when VCaP scr shRNA and VCaP ERG shRNA tumors reached similar size as per luciferase signal in the bone tumors. a Intratibial tumor growth of luciferase expressing VCaP scr shRNA and VCaP ERG shRNA cells and treatment with vehicle control or enzalutamide. b Comparison of tumor growth of vehicle treated VCaP scr shRNA and VCaP ERG shRNA tumors. c Comparison of tumor growth of enzalutamide treated VCaP scr shRNA and VCaP ERG shRNA tumors. d Luciferase imaging of bone tumors