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. 2019 Sep 20;20(19):4661. doi: 10.3390/ijms20194661
AA amino acids
NFTs neurofibrillary tangles
NDs neurodegenerative diseases
BSE bovine spongiform encephalopathy
CJD Creutzfeldt-Jakob disease
AD Alzheimer’s disease
HD Huntington’s disease
PD Parkinson’s disease
amyloid beta
AβOs oligomers of amyloid β peptide
LTP long-term potentiation
LTD enhanced long-term synaptic depression
LMW low molecular weight
HMW high molecular weight
MT Microtubule
MAP microtubule-associated proteins
PRD proline-rich domain
MBD microtubule binding domain
PNS peripheral nervous system
PSP progressive supranuclear palsy
CBD cortico-basal degeneration
CNS central nervous system
PHFs paired helical filaments
hTau hyperphosphorylated Tau
MARK microtubule affinity regulating kinase
Cdk5 cycline-dependent kinase 5
GSK3b glycogen synthase kinase 3b
NMDAR N-methyl-d-aspartate receptor
AMPAR α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
IDP intrinsically disordered protein
NGF nerve growth factor
ROS reactive oxygen species
IGF-1 insulin-like growth factor-1
IRS-1 Insulin receptor substrate 1
PTEN phosphatase and tensin homologue on chromosome 10
TauOs oligomers of Tau protein
SF straight filaments
PSD-95 post synaptic density 95 protein
MMSE Mini Mental State Examination test
MRI magnetic resonance imaging
PET positron emission tomography
CSF cerebrospinal fluid
NFL neurofilament light protein
scFvs single chain antibody fragments
MMPs matrix metalloproteinases
MCI mild cognitive impairment
TTR transthyretin
ATTRwt wild-type amyloidogenic transthyretin
ATTRv variant amyloidogenic transthyretin
TTR-FAP transthyretin-related familial amyloid polyneuropathy