AA |
amino acids |
NFTs |
neurofibrillary tangles |
NDs |
neurodegenerative diseases |
BSE |
bovine spongiform encephalopathy |
CJD |
Creutzfeldt-Jakob disease |
AD |
Alzheimer’s disease |
HD |
Huntington’s disease |
PD |
Parkinson’s disease |
Aβ |
amyloid beta |
AβOs |
oligomers of amyloid β peptide |
LTP |
long-term potentiation |
LTD |
enhanced long-term synaptic depression |
LMW |
low molecular weight |
HMW |
high molecular weight |
MT |
Microtubule |
MAP |
microtubule-associated proteins |
PRD |
proline-rich domain |
MBD |
microtubule binding domain |
PNS |
peripheral nervous system |
PSP |
progressive supranuclear palsy |
CBD |
cortico-basal degeneration |
CNS |
central nervous system |
PHFs |
paired helical filaments |
hTau |
hyperphosphorylated Tau |
MARK |
microtubule affinity regulating kinase |
Cdk5 |
cycline-dependent kinase 5 |
GSK3b |
glycogen synthase kinase 3b |
NMDAR |
N-methyl-d-aspartate receptor |
AMPAR |
α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor |
IDP |
intrinsically disordered protein |
NGF |
nerve growth factor |
ROS |
reactive oxygen species |
IGF-1 |
insulin-like growth factor-1 |
IRS-1 |
Insulin receptor substrate 1 |
PTEN |
phosphatase and tensin homologue on chromosome 10 |
TauOs |
oligomers of Tau protein |
SF |
straight filaments |
PSD-95 |
post synaptic density 95 protein |
MMSE |
Mini Mental State Examination test |
MRI |
magnetic resonance imaging |
PET |
positron emission tomography |
CSF |
cerebrospinal fluid |
NFL |
neurofilament light protein |
scFvs |
single chain antibody fragments |
MMPs |
matrix metalloproteinases |
MCI |
mild cognitive impairment |
TTR |
transthyretin |
ATTRwt |
wild-type amyloidogenic transthyretin |
ATTRv |
variant amyloidogenic transthyretin |
TTR-FAP |
transthyretin-related familial amyloid polyneuropathy |