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. 2019 Sep 28;20(19):4830. doi: 10.3390/ijms20194830

Figure 4.

Figure 4

Curcumin ameliorates the C. jejuni-induced barrier dysfunction in colon of IL-10−/− mice. Colon specimens of IL-10−/− mice were mounted in Ussing chambers designed for impedance spectroscopy. (A) Epithelial conductance (G) (n = 5–18, *** p < 0,001, Mann–Whitney U-test) and (B) fluorescein (332 Da) permeability (n = 5–14, * p < 0.05, Mann–Whitney U-test) of IL-10−/− mouse colon were measured in Ussing chambers. IL-10−/− mice were either infected with C. jejuni (per oral gavage with 10 8 CFU in 0.3 mL) or infected and treated for 6 days with Curcumin (0.5 mg/mL).