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. 2019 Oct 17;145(12):1170–1178. doi: 10.1001/jamaoto.2019.3020

Table 5. Variables Associated With Moderate to Severe Decision Regret on Univariate Analysis.

Variable Moderate to Severe Decision Regret, OR (95% CI)
Age, y
50-64 1 [Reference]
≥65 0.88 (0.45-1.70)
Marital status
Married or common-law marriage 1 [Reference]
Other 0.67 (0.30-1.48)
Educational level
No postsecondary education 1 [Reference]
Postsecondary education 0.89 (0.44-1.80)
Clinical stage
0, I, or II 1 [Reference]
III or IV 2.03 (0.87-4.78)
Microvascular reconstruction
No 1 [Reference]
Yes 0.86 (0.41-1.83)
Tumor site
Nonmucosal 1 [Reference]
Mucosal 1.37 (0.69-2.69)
Surgical complications
No 1 [Reference]
Yes 1.70 (0.82-3.51)
Disease recurrence
Alive without disease 1 [Reference]
Alive with disease 0.59 (0.22-1.59)
Vulnerable Elders Surveya 1.19 (0.93-1.52)
Lawton-Brody IADL Questionnairea 0.85 (0.75-0.97)
Fried Frailty Indexa 1.38 (1.01-1.90)
Bradburn Scale of Psychological Well-Being (happiness)a 0.78 (0.68-0.91)
Geriatric Depression Scalea,b 1.17 (1.06-1.28)
EORTC QLQ-C30a
Preoperative 1.03 (1.01-1.05)
6 mo After surgery 1.07 (1.04-1.10)

Abbreviations: EORTC QLQ-C30, European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire; IADL, instrumental activities of daily living; OR, odds ratio.

a

Odd ratio per unit or 1-point increase.

b

On multivariate analysis for moderate to severe decision regret, only preoperative Geriatric Depression Scale remained significant (P = .001).