Table 1. Comparison of MMRV, MMR and Varicella (Var.) Vaccines by manufacturer.
Manufacturer | GlaxoSmithKline (GSK) Inc. | Merck Inc. | ||||
---|---|---|---|---|---|---|
Vaccines |
MMR (PriorixTM) |
Var. (VarilrixTM) |
MMRV (Priorix-TetraTM) |
MMR (MMR-IITM) | Var. (Varivax-IIITM) | MMRV-U.S. (ProQuadTM) |
Authorized for use in Canada | Yes | Yes | Yes | Yes | Yes | No** |
Measles strain | Schwarz ≥ 3,3 log10 CCID50 |
Nil | Schwarz ≥ 3.0 log10 CCID50 |
Enders (Edmondston) ≥ 3.0 log10 CCID50 |
Nil | Enders (Edmondston) ≥ 3.0 log10 TCID50 |
Mumps strain | RIT4385JL* ≥ 3.7 log10 CCID50 |
Nil | RIT4385 JL ≥ 4.4 log10 CCID50 |
JL (B level) ≥ 3.7 log10 CCID50 |
Nil | JL ≥ 4.3 log10 TCID50 |
Rubella strain | Wistar RA 27/3 ≥ 3.0 log10 CCID50 |
Nil | Wistar RA 27/3 ≥ 3.0 log10 CCID50 |
Wistar RA 27/3 ≥ 3.0 log10 CCID50 |
Nil | Wistar RA 27/3 ≥ 3.0 log10 TCID50 |
Varicella strain | Nil | Oka ≥ 3.3 log10 PFU |
Oka ≥ 3.3 log10 PFU |
Nil | Oka-Merck ≥ 3.13 log10 PFU |
Oka-Merck ≥ 3.99 log10 PFU |
Age group | ≥ 12 mos. | ≥ 12 mos. | ≥ 9 mos.*** - 6 years of age**** |
≥ 12 mos. | ≥ 12 mos. | 12 mos.–12 yrs. |
Storage | Refrigerator | Refrigerator | Refrigerator | Refrigerator | Refrigerator | Freezer |
* JL = Jeryl Lynn mumps vaccine strain. ** ProQuadTM is not authorized in Canada as of September 2009 (shown here to allow comparison of the minimum potencies of vaccine antigens). *** Authorized for use at 9 to 11 months of age, but not recommended by NACI. **** May be used in individuals up to 12 years of age based upon previous experience with separate component vaccines PriorixTM and VarilrixTM.