Table 11. Varicella Antibody Persistence Rates and GMTs for Subjects Who Seroconverted 6 Weeks after Vaccination.
MMR II + varicella vaccine co-administered | MMR II + varicella vaccine given 6 weeks apart | |||
---|---|---|---|---|
Persistence rate % | GMT (95% CI) | Persistence rate % | GMT (95% CI) | |
1 year | 100 | 35.3 | 98.2 | 25.7 |
(143/143) | (28.4-44.0) | (109/111) | (20.0-33.0) | |
3 years | 98.8 | 40.0 | 99.1 | 36.8 |
(82/83) | (28.7-55.9) | (112/113) | (27.4-49.3) | |
4 years | 99.0 | 34.4 | 100 | 29.1 |
(95/96) | (25.6-46.4) | (76/76) | (20.1-42.3) | |
5 years | 100 | 49.5 | 100 | 40.2 |
(91/91) | (35.5-69.0) | (77/77) | (27.9-57.9) | |
6 years | 100 | 42.9 | 98.6 | 31.3 |
(91/91) | (31.9-57.7) | (70/71) | (20.9-46.8) |
Source: Shinefield HR et al. Vaccination with measles, mumps and rubella vaccine and varicella vaccine: safety, tolerability, immunogenicity, persistence of antibody and duration of protection against varicella in healthy children. Pediatr Infect Dis J. 2002; 21: 555–61