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| Reaction | First vaccination | Second vaccination | Third vaccination | |||
|---|---|---|---|---|---|---|
| Fluad® (n=2112) | Comparator (N=1437) | Fluad® (N=492) | Comparator (N=330) | Fluad® (N=150) | Comparator (N=87) | |
| Malaise* | 6% | 4% | 8% | 7% | 7% | 3% |
| Headache** | 6% | 4% | 8% | 7% | 7% | 3% |
| Myalgia*** | 8% | 3% | 3% | 2% | 1% | 2% |
| Fever (≥38oC) | 1% | <1% | 1% | 1% | 1% | 0% |
Differences between Fluad® and comparator vaccine for the first vaccination only: *p=0.003; **p=0.010; ***p<0.001
