Table 6. Immunogenicity of HPV4 vaccine (Gardasil®) among males 16 to 26 years (n=2025) (114).
Assay (cLIA v2.0) | HPV4 (n=2025) | |||
---|---|---|---|---|
Geometric mean titre (GMT) | 95% CI | Seroconversion rate | 95% CI | |
Anti-HPV type 6 | ||||
Day 1 | <7 | <7-<7 | 0.0 | 0-0.3 |
Month 7 | 446.0 | 422-474 | 98.9 | 98-99 |
Month 24 | 80.3 | 76-85 | 90.8 | 89-93 |
Anti-HPV type 11 | ||||
Day 1 | <8 | <8-<8 | 0.0 | 0-0.3 |
Month 7 | 624.2 | 594-656 | 99.2 | 98-100 |
Month 24 | 94.5 | 90-100 | 95.6 | 94-97 |
Anti-HPV type 16 | ||||
Day 1 | <11 | <11-<11 | 0.0 | 0-0.3 |
Month 7 | 2402.5 | 2271-2542 | 98.8 | 98-99 |
Month 24 | 347.8 | 329-367 | 99.3 | 99-100 |
Anti-HPV type 18 | ||||
Day 1 | <10 | <10-<10 | 0.0 | 0-0.3 |
Month 7 | 402.2 | 380-426 | 97.4 | 96-98 |
Month 24 | 38.7 | 36-41 | 62.3 | 59-65 |