Figure 2.

The effects of sh-PVT1 on the proliferation ability of pituitary adenoma cells. (A) Statistical analysis for plasmid transfection efficiency. (B) Higher PVT1 expressions in pituitary adenoma cell lines (HP75 and GH3) were downregulated by the transfection of specific shRNAs. (C, D) MTT and colony formation assays were used to examine the proliferation ability of pituitary adenoma cells after PVT1 was knocked down. Means ±SDs of results obtained from at least 3 experiments are shown. ** p<0.05 vs. Normal control (NC) group.