Figure 3.

Clock genes and transcription factors involved in lipid metabolism showed little changes in mRNA levels in rats fed an HSD. a–h, diurnal mRNA level variations of several important clock genes in maintaining metabolism hemostasis (n = 4/group at each time point). i–l, diurnal mRNA level variations of key transcription factors involved in lipid metabolism (n = 4/group at each time point). Rhythmic analysis was performed with JTK_CYCLE, and the results are shown in Table S2. Error bars, S.D.