Table 2.
Respiratory Exacerbations Before And After Combination Therapy With Nebulized Colistin And Continuous Cyclic Azithromycin. For Differences Between Periods, See Table 3–5
| Variable | No Nebulized Colistin (Baseline) | Long-Term Nebulized Colistin Plus Azithromycin | |
|---|---|---|---|
| Prior 12 Months (n:32) | 0-12 Months (n:32) | 12-24 Months (n:24) | |
| Exacerbation | |||
| - Total (n) | 126 | 76 | 57 |
| - Median per year [IQR] | 4 [3-5] | 2 [1-3.2] | 2 [1-4] |
| - Median per month [IQR] | 0.33 [0.25-0.42] | 0.17 [0.08-0.35] | 0.17 [0.14-0.33)] |
| Hospitalization | |||
| - Total (n) | 85 | 46 | 35 |
| - Median per year [IQR] | 3 [1-4] | 1 [0-2] | 1 [0-3] |
| - Median per month [IQR] | 0.25 [0.08-0.33] | 0.08 [0-0.17] | 0.08 [0-0.25] |
| Hospital stay (days) | |||
| - Total (n) | 1625 | 1108 | 595 |
| - Median per year [IQR] | 49 [14.5-70] | 9 [0-49.2] | 20.5 [0-45.2] |
| - Median per month [IQR] | 0.13 [0.04-0.19] | 0.05 [0-0.13] | 0.06 [0-0.13] |
Abbreviation: IQR, interquartile range.