Table 6.
Number Of Microbiological Isolates And Percentages Adjusted Per Total Number Of ECOPD Before And After Combination Therapy With Nebulized Colistin And Continuous Cyclic Azithromycin
| Microbiological Isolates Number (%ECOPD) | No Nebulized Colistin | Long-Term Nebulized Colistin Plus Azithromycin | |
|---|---|---|---|
| Number Of Isolates Prior 12 Months (n:32) ECOPD n:126 |
Number Of Isolates 0-12 Months (n:32) ECOPD n: 76 |
Number Of Isolates 12-24 Months (n:24) ECOPD n: 57 |
|
|
Group 1: Common potentially pathogenic microorganisms |
18 (14.2) |
9 (11.8) |
10 (17.5) |
| H.influenzae | 4 (3.2) | 1 (1.3) | 1 (1.7) |
| S. pneumoniae | 5 (3.4) | 5 (6.6) | 7 (12.3) |
| M. catarrhalis | 9 (7.1) | 2 (2.6) | 0 (0) |
| MSSA | 0 (0) | 1 (1.3) | 2 (3.5) |
|
Group 2: MRSA |
0 (0) |
1 (1.3) |
2 (3.5) |
|
Group 3: P.aeruginosa |
75 (59.5) |
21 (27.6) |
14 (24.6) |
|
Group 4: Other Gram-negative bacteria |
7 (5.5) |
9 (11.8) |
5 (8.7) |
| S.maltophilia | 1 (0.7) | 0 (0) | 3 (5.2) |
| A.xylosoxidans | 6 (4.7) | 8 (10.5) | 1 (1.7) |
| S.marcescens | 0 (0) | 0 (0) | 0 (0) |
| E. coli | 0 (0) | 1 (1.3) | 1 (1.7) |
| P. mirabilis | 0 (0) | 0 (0) | 0 (0) |
Abbreviation: ECOPD, chronic obstructive pulmonary disease exacerbation.