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. 2019 Oct 17;12:2145–2155. doi: 10.2147/DMSO.S223842

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© 2019 Sun et al.

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JMT decreased IL-1β and IL-18 expression in serum and SNs of diabetic rats.

Notes: Representative staining of IL-1β (magnification, ×400) (A–D). Brown color corresponds to protein of interest, and blue color corresponds to nuclear staining. Normal control (A), Diabetes (B), Diabetes + JMT (C), Diabetes + ALA (D). Quantitative analysis of positive-stained areas relative to total tissue areas (E). Representative Western blot images of IL-1β (F). Densitometric analysis of IL-1β/β-actin protein expression normalized to the normal control group (G). Serum IL-1β and IL-18 levels analyzed using ELISA (H, I). Data are the mean ± SEM from three independent experiments. ***P < 0.001 vs normal group, ^###P < 0.001 vs diabetes group.

Abbreviations: JMT, Jinmaitong; IL, interleukin; SN, sciatic nerve; ALA, alpha-lipoic acid; ELISA, enzyme-linked immunosorbent assay; SEM, standard error of mean.