Table 4.

Former control group PSG results by months of active therapy (per protocol population)

	Baseline (n = 73)	6-month active therapy (n = 65)	12-months active therapy (n = 61)	18-month active therapy (n = 59)
Proportion with 50% reduction in AHI from baseline [% (95% CI)]	N/A	55% (43% to 67%)	52% (40% to 64%)	53% (40% to 65%)
AHI (events/hour)	42 [32, 60]	18 [8, 32]	22 [10, 34]	17 [6, 30]
CAI (events/hour)	22 [10, 35]	2 [0, 5]	1 [0, 5]	1 [0, 3]
OAI (events/hour)	2 [1, 4]	2 [1, 8]	3 [1, 10]	2 [1, 7]
MAI (events/hour)	1 [0, 5]	0 [0, 1]	0 [0, 1]	0 [0, 1]
HI (events/hour)	11 [4, 18]	7 [3, 15]	9 [4, 19]	8 [3, 18]
ODI4 (events/hour)	39 [26, 57]	17 [7, 30]	18 [9, 32]	15 [5, 27]
ArI (events/hour)	37 [25, 56]	19 [13, 30]	19 [14, 34]	17 [12, 35]
Sleep with oxygen saturation <90% (%)	8 [2, 19]	4 [1, 16]	4 [1, 11]	4 [0, 15]
Sleep with oxygen saturation <90% (min)	28 [8, 63]	13 [2, 36]	11 [3, 27]	13 [2, 33]
Percent of sleep in REM	11 [6, 16]	16 [10, 20]	16 [7, 22]	16 [9, 21]

Continuous variables reported as median [interquartile range]. CI = confidence interval; N/A = not applicable; ODI4 = oxygen desaturation ≥4% index.