Fig. 5. Colons of Cdx2-Ano1^fl/fl mice in steady state depict mild edema.

a Hematoxylin and eosin staining of colons from Ano1^fl/fl (WT) and Cdx2-Ano1^fl/fl (CKO) mice (Swiss roll preparation). There was marked thickening of the mucosal layer (arrowheads) and submucosal edema. b Water content in the stool was significantly increased in the CKO mice. The water content in the stool was measured by dividing the wet weight minus the dry weight by the wet weight of the stool. *p < 0.05. Error bars represent the SEM. The numbers in brackets represent the number of experiments