Table 3.
Comparison of the urine indexes of mice in each group
| sh-NC | sh-PVT1 | GSK126 | sh-PVT1 + sh-FOXA1 | |
|---|---|---|---|---|
| Brine volume (μL) | 1475 ± 432 | 828 ± 516* | 799 ± 336* | 1535 ± 513 |
| Blood sugar (mmol/L) | 22.95 ± 4.76 | 7.59 ± 1.11* | 8.45 ± 1.01* | 24.07 ± 5.08 |
| Plasma urea nitrogen (mmol/L) | 6.38 ± 1.61 | 3.65 ± 0.25* | 2.92 ± 0.43* | 7.25 ± 0.85 |
| Urine protein/urine creatinine ratio | 103.27 ± 10.58 | 31.11 ± 2.13* | 34.31 ± 3.82* | 110.53 ± 12.66 |
| Renal weight/body weight ratio (mg/g) | 12.68 ± 0.97 | 7.76 ± 0.42* | 7.21 ± 0.28* | 13.64 ± 1.22 |
NC negative control, PTV1 plasmacytoma variant translocation 1, GSK126 EZH2 inhibitor, FOXA1 forkhead box A1
*p < 0.05 vs. the sh-NC group; n = 10