4. Original Alere LAM review, main findings.

Type of analysis	Symptomatic participants			Unselected participants
	Studies (total participants)	Pooled sensitivity (95% CrI)	Pooled specificity (95% CrI)	Studies (total participants)	Pooled sensitivity (95% CrI)	Pooled specificity (95% CrI)
Overall accuracy	5 studies (2313)	45% (29% to 63%)	92% (80% to 97%)	3 studiesa (1055 )	30% (20% to 43%)	94% (86% to 97%)
By setting
Inpatient	4 studies (1299)	53% (38% to 70%)	90 % (73% to 96%)	Insufficient data
Outpatient	Insufficient data			Insufficient data

Abbreviations: LF‐LAM: lateral flow urine lipoarabinomannan assay (Alere Determine™ TB lipoarabinomannan assay); Crl: credible interval

Main findings from the original review on LF‐LAM accuracy (Shah 2016).
 ^aReported at grade 1 on the previous reference scale card with five bands that is outdated and no longer the recommended positivity threshold.