Table 4.
Results of paired permutation tests comparing treatment outcome measures and standardized tests at each time point relative to pre-treatment and post-treatment for all participants (both clinical variants and both treatment dosage groups).
| Pre-treatment performance vs. |
Post-treatment performance vs. |
|||||||
|---|---|---|---|---|---|---|---|---|
| Post-treatment | 3-month follow-up | 6-month follow-up | 12-month follow-up | 3-month follow-up | 6-month follow-up | 12-month follow-up | ||
| Trained | n | 18 | 16 | 16 | 17 | 16 | 16 | 17 |
| t | −17.8 | −11.5 | −24.9 | −8.4 | 2.7 | 2.2 | 3.6 | |
| p | < 0.001* | < 0.001* | < 0.001* | < 0.001* | 0.013* | 0.714 | 0.031 | |
| Untrained | n | 18 | 16 | 16 | 17 | 16 | 16 | 17 |
| t | −3.1 | −3.6 | −2.6 | −1.3 | −0.1 | 0.4 | 1.6 | |
| p | 0.003* | < 0.001* | < 0.001* | 0.448 | 0.967 | 0.723 | 0.129 | |
| BNT | n | 18 | 15 | 14 | 14 | 16 | 14 | 15 |
| t | −1.9 | 0.8 | 2.4 | 3.0 | 1.5 | 4.2 | 3.7 | |
| p | 0.003* | 0.427 | 0.053 | 0.053 | 0.714 | 0.012* | 0.027 | |
| WAB | n | 18 | 16 | 16 | 15 | 16 | 16 | 15 |
| t | −0.1 | 2.4 | 3.2 | 5.1 | 3.7 | 3.7 | 5.5 | |
| p | 0.724 | 0.061 | 0.061 | < 0.001* | 0.013* | 0.003* | < 0.001* | |
| MMSE | n | 18 | 15 | 16 | 15 | 15 | 16 | 15 |
| t | −0.2 | −0.2 | 1.9 | 3.0 | 0.9 | 2.8 | 4.0 | |
| p | 0.868 | 0.934 | 0.090 | 0.004* | 0.408 | 0.008* | < 0.001* | |
Note. One-tailed tests were used for trained items for all comparisons to pre-treatment performance. All other comparisons utilized two-tailed tests. Trained = trained items; Untrained = untrained items; BNT= Boston Naming Test; WAB = Western Aphasia Battery.
Bonferroni-corrected thresholds for significance: p < 0.013 for comparisons to pre-treatment performance and p < 0.017 for comparisons to post-treatment performance.