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. 2019 Oct 10;10(1):459–468. doi: 10.1080/21655979.2019.1676485

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Chemoresistant colorectal cancer samples express high levels of SREBP1. a, Representative image of immunohistochemical staining for SREBP1 in chemosensitive and chemoresistant colorectal cancer (CRC) samples. Scale bars: 100μm. b, Statistical analysis revealed IHC scores between the two groups were significantly different (P = 0.001). c, d, Kaplan-Meier survival curves of overall survival duration based on SREBP1 expression in CRC tissues. The receiver operating characteristic curve was used to define the cutoff, and log-rank analysis was used to test for significance.