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DAPA reduced the lipid content and pathological changes in the liver of DM mice. (A) Histological analysis of liver tissues by Oil red O staining; (B) the percentage of Oil red O positively stained area was analyzed by Image-pro plus 6.0; DAPA alleviated TG (C) and FFAs levels (D) in the liver of DM mice; . DAPA, dapagliflozin; DM, diabetes mellitus; NDM, non-diabetes mellitus; TG, hepatic triglyceride; FFA, free fatty acid.
