Table 4. Comparison of the OPRM1 gene A118G genotype and allele distributions in the two groups.
| Group | N | Genotype frequency, n (%)a | Mutant frequency, n (%)b | Allele frequency, n (%)c | |||||
|---|---|---|---|---|---|---|---|---|---|
| A/A | A/G | G/G | A/G + G/G | A | G | ||||
| Hemorrhage group | 167 | 73 (43.7) | 82 (49.1) | 12 (7.2) | 94 (56.3) | 228 (68.3) | 106 (31.7) | ||
| Non-bleeding group | 163 | 89 (54.6) | 68 (41.7) | 6 (3.7) | 74 (45.4) | 247 (75.5) | 83 (24.5) | ||
a, comparison of genotypes: χ2=4.839, df=2, P=0.089; b, comparison of wild type and mutant: χ2=3.913, df=1, P=0.048; c, comparison of alleles: χ2=4.222, df=1, P=0.04, OR: 1.549, 95% CI: (1.003–2.391). OR, odds ratio; CI, confidence interval.