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Kinetics changes of Bregs in liver transplant recipients with stable allograft liver function and acute rejection are shown. CD19+CD24hiCD38hi transitional Breg (A) and CD19+CD24hiCD27+ memory Breg (B) cell frequencies are expressed as a percentage of the total CD19+ B cell population. Representative flow cytometry readout demonstrating CD19+CD24hiCD27+ memory Breg in one patient from AR group (C). *, P<0.05 SF vs. AR, at time points of 1w, 2w & 4w.
